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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f3715dae88f0953c0a19547e6d56dadfe76a728a900816ea359c8b42a944a5' 
  AND token = 'ESc8i2lBtAeDSGuy2aE0MWsV9aK/0xIx9InoEflsHZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}