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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3a10a8362de12392eaa2dcd106910f60e096b5635416978056bed1676f2287' 
  AND token = 'mHR1iU/ujYfsWqZVzNug7B7GoItIlfs5YWHoLNHc334=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}