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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42853f9aad44f252b89ea6a5d0e5e6579690a91fa8755b24b55e98ee8fd7c8dd' 
  AND token = 'ETQCoN7qBzHSDccGuXyNg334LYG8sBn9IdZNKiqZZg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}