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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc5d1645287854673ffcb8f4c0bc2d2b98b1eb27097c59ffe078674d590e7c66' 
  AND token = 'H9+OxeZyNxhgXnSVhTtg9fV1nVEmAyWWcDM4Bo8AsSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}