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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18ab775745b714415f9e2416d01c51fc42fa41a10aba72bd377a7c1c0808750' 
  AND token = 'tLS3f4vr+ldzRdEKupEvGXPpr5AM4SGZyo9e4/3asw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}