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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7a22f67e2936b7fddb026e635403bbd7e32db3ea25251557701ce72c56ff0c' 
  AND token = 'hfMBuo3PSmsFi6jF1lPSD4N+u3R+bmHDEK5rqMVPR+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}