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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b11daef79f0ba1ac634ad2aa7a10a6b9340d026c8440fee9e50265bde191004' 
  AND token = 'g8660qfEp+7G+U1OgRb6b3/Z3E4rHRfrj2Ek8d/Xv4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}