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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ca17520b901d71da5f2949e00ae85786a3d1bfda76bfa418cfa643d7ff3fe3' 
  AND token = 'HC5JGDJymySMswpkEpEbswDt7cYqZ1LGp1gvmA6ou14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}