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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b199f83dada2e5b4dddf213dfcfc34c75f214f53ef58f95aef1916c1aeb3ebf' 
  AND token = '/xuYZo4iSu9btqm7HcSESnEeJwdQyQedR5ZS4lMvnUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}