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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b62db0135618b1c6afdd6b62b22292c48b2365b6da8707288e56a4989465aef' 
  AND token = 'HXowboiZAjYouT+gkEOvOoRo6j+ZTyb0+BklwN90SNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}