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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4205b03c8f302be5d5866eaafc3bc63d0e9490ac9ee8378a0079b9354f041b3f' 
  AND token = 'CODY3KdDCTALCSR+4Kz9CJo+dX4tSJFIPEzc+NWluz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}