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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2997238299ad2ce1ef3c866454d31f04e7c96a9b4c3e80d37c8f0a5faf9d6a2c' 
  AND token = 'Oc7v69x5Vv0X7coE+7vQbQwDaxoMa9FOQGeSTUUpgv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}