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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9009be3c9a5caae58b021bd9d786a83dfab421dd43fdf5e6bfa82d1d8b5a37f2' 
  AND token = 'xUaLJRtB8feRgCnvXxz8sW6ycsYUc+o3yDXuzeyoZPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}