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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59235af864793a66b016cae3e9ebef6623c81d0abeb56b463e460b57b4240f9' 
  AND token = 'Uqq3TrO05rLyxQSbyaYQjeqoKIUzgHS9HLJ6yu9XIFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}