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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54efdbe31a74b1eb8f6f6f0a8f6179522aef22bec38490a1f0c8fcc7b8de6c45' 
  AND token = 'zEG/5tGcPVwmm/wfOi4uCd6MrFNjnretD8yCXs2XFes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}