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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2ad78eb65ad7dc10193854e64ac7175eabd8fdd26a55e83b2c47c60b2483ae' 
  AND token = 'u+KyA21sQ/Z/lTV+XqP2H1D8VzrWEy7dg/nlhoZZBAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}