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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff812d699d31020824e183dbdbf549cf05121e6c5f565620b8a77f4cd10a7fa' 
  AND token = 'HpQCu3eapJ8DhapJ4nMsrmTVY04WcQ3maxxVgJxjd1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}