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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e88175f0de33fd260d0e826f631f1398854cfa5af0d2a333100c2dc166cf0b6a' 
  AND token = '7KbYAlBrEzaIaNUB3LqeavIwdnwa3B6rxJK+NqDm42k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}