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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6dc243dc4c3cb4b8a5001eca2b2ea2ef2228935ae8f602a1e545e064ae2da69' 
  AND token = 'GyjwQRWVB9J25x7+FV33bsyoiXZtfZ9Mh+Az0PoQkVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}