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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d03102353a0b3d8c6c158aeab5141e57f98df2ac63ad1a4ffa29c022c64663' 
  AND token = 'nBLPnVmTC2D2SC2mMH1+e7D5lAvyj0/wxsRfLSlZb3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}