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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf3b6eb4b29a578e34996660fd2f804253f3354e9d5aa53932c57411f7a4633' 
  AND token = 'LXfKa6FHARYAMsf8EpdkO33odxp3mENgY68/jrXhVxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}