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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4bfd9d4aaa84ffac76bd6829ab7648c8202ab8547c37a23cf1964e7ac82a85' 
  AND token = 'XBR/VA8nAGaTfi/DNQ7+muBv1EtDYgDWbQNpL6s2dlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}