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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69d400b967016cf2759ea709cba805c2dd5adaee5e317258b38b6d5d0292e2ec' 
  AND token = 'Fz9MctVtoEtI6RPzaZTVI17OBRriCTBdWloWhxY2EFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}