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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785d3dd00db509dc0cd1b5b0a61121c29b651b0e2032a1beffba479121647444' 
  AND token = 'gYmlmKwYr4W1BWXpGAh4TN+p2TBbcmoptvB5Mdt0LP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}