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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f94677387f297c053a7e425e7529ff7f3cbea24ff69352a1483056205c58b7e5' 
  AND token = 'EbeMIix9V5GoepY3L6nIxV5OLUqXhb1hNSTSLIYpxJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}