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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7b123166a22a5397c72976140ee745e4916c044e1026b640de5e4ead93ee18' 
  AND token = 'MVEn+xsaLgl1ArbjfPQvJaFaQUH0dkgr5l78X6yNlNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}