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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d6e7121e3474a9f1a1785eb00728949357039df7893f5dec03a3b00876c980' 
  AND token = 'oYuFQC2iTXiyiS64Jn8NF7th+E9F5Rna32J4vVGgWz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}