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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccc3fc649e7c813c5a3e05be5c4398e87e1d55afc7c46b6bb0abb254f32153aa' 
  AND token = '1GC4W4tp4B6kMtDpcFauP6LkkyIDpyk3nzcNiKbVOvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}