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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1a89a780b7f907159eb09059615ac3d58336781ef7a3c657027dd8f2faddb9' 
  AND token = 'Po+aWAw0lMJHJSp3QcDC1d7rDSJ9Xqj8mm6Fc9Zx4n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}