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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a224bbca3004599de70d6974ef44eb2b7fb5b7de5f70f6370c9790f894e6457' 
  AND token = '3GWmc8mRlg6iZD9nbFP6dQhg2VmRZNOQRSw9xLFgk00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}