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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db9eb7f158dc85aadde9fc544acf8e75fc5a6781b344a110e8092d088fc415e' 
  AND token = 'r5GfSpVdnbKM0J9aiqSWfDGQgQf2v/ji8MOBJBjvBxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}