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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0c4eed0d220f4adf3e86b03a80c46f9a0daa6342003d657436b06634538aea' 
  AND token = '9sLND7zvx4JRckYoPpP8wWu1+RTzer5Lkyw959vXWT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}