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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '924da91c85957133fc7b369809f4cf11306f4dd3aa67f43a6b7cecacdbda0bc7' 
  AND token = 'DQ1jezEaRB6iD+rRK7FYPQf20/c4wc/t6cNCD4IOvxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}