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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5717acf64d92f3dd041a0e75bcef801dd9eb9986fdac6530d350e6aa0ff4ed2a' 
  AND token = 'UesRKsmX21kUfXT5y9SXL0UFJEO2Ic6aIar3DrI48Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}