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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a9b59b4cb097fd2da6a0205f0433d135a86e34e19f570c48543d7e00f8ff45' 
  AND token = 'x+gJvx+DrpyLicv5/Va5AIs62JXvNAvB8EczlYcxOyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}