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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b8fa08c05328dac4088c17f6d3e2c7a89041ef881bf78252add9c7ef64de2e' 
  AND token = 'vOJx5LubF64q0H0qZSlx//ruHRcfBmgYhmeZ0rpVWt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}