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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a50f89ff6882d621464e7790cb5147dfb2d4a73e391dc9d68730fdea5c60c60' 
  AND token = 'ZW4muaMuNYKu3SuZJM1jwAUSSrKHPFMoWGZ3J4s7HPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}