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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a525d24b2413ae1c6e283c8ea52b9b547fdb6969d89c8a875bb451c7b2e006c' 
  AND token = 'l/ST+5wN7VnmePtc7Nf8rY1y4DprtmeHN7IE9Bv/pl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}