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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b34cf2c24e06579ff1fb888b251f19ca6a0c2ade7fffcb4083106c1d087342' 
  AND token = 'YxrntyEdj/C+i9SrS4SFk6eyItzTtOblYiZdrZw2nAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}