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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0c6cb80b6e8a2d7f44db59c3f2b3789c5d7fac1d16f090e6f83567b322fd41' 
  AND token = 'VmnnzHffiw738xg5oCJTc+Dh71EzkQ4BzyjYaEmxzj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}