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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a190d64b1d66ef938671c13b80d2d93124308440d3e3492063f99378c0fc84' 
  AND token = 'EIR2dSbrCYsHdHcUyom0Rbr5Jj5ZlwV+A250DbsMr8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}