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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e695e0a3f5e9d232f5224e59195e3887f655673e2c69bdf2df5a220892e7b4b' 
  AND token = 'qSTs1WEI3+JRion73mam2YQPeq3E4EGmfPK6IBf62Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}