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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b85eee247096bc66cbb869ce3b1f16b1af8f1eb63c18a68f44054e627e180c56' 
  AND token = 'Z5a/2CePh4ZFx4YtT+dNHxuqUzF/1Or9NMDvrSyk3yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}