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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716e1ce89061154627e2e8d38fcd242492808a3797f6f85710398a76256b77e8' 
  AND token = 'pmuvZJRI1ZQ4j2sssXJGyWYigcygRPEBaEuhc4H6gmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}