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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60464c6178017d81632472c5cb0230465a823c4ce46a90835149e7aed38d6d3a' 
  AND token = 'VmVEcGe4oOEjM59nqmeeve8ug8r1KYBYS0XUX2/dWts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}