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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffb5e7c8760e01d8b6155cbb0cf708f022c39e67d632b414fa72d0b89115842' 
  AND token = 'VxHOKJUtFBJXuaAgmQ9iNXTCozRdM9iBCWUc6foDwnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}