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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c2507ef10e56e321bae2cabac20adc94a7058554a8c8b1eb677b8ee2f7c508' 
  AND token = 'Wu4UG+YBL0t1raM2tMkpHrIiGe83nC6zbzRSy2voNis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}