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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b8c01bb124d39e199174322b1675dd3241ba0835ff8d88d9abc81d4b8c9624' 
  AND token = 'ekH/qdnGjJ7/jcxB+TbEFQBqDD7gADUDgNgdWsvD60E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}