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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb7e41602abd366d4de71bdbd439cd95381b741d10b282f4d246d60f16a6011' 
  AND token = 'NBbb7bBZhKESJB+mi5ap+vs3QA9m3srVYe3WU0Y/gr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}