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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c776821131a26b5dee8bdac1d3ac614bd5b7976ce0ccf013895867d0012c687' 
  AND token = 'XFrN9KH8ToDns6geUhD47CxLtu6Bt0QgzIerk3kxOHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}